Cellular Microscopic Appearance (~10-6m)
  • Large number of irregularly shaped dividing cells
  • Large, variably shaped nuclei
  • Small relative cytoplasmic volume
  • Loss of normal specialized cell features
  • Disorganized arrangement of cells
  • Angiogenesis
  • Tissue Expressions Within Ultrasound Resolution (>10-5m)
  • Poorly defined tumour boundaries
  • Irregular shapes
  • Increased local perfusion
  • Tissue stiffening
  • Histoscanning 2 Stage Tissue Differentiation Analysis
  • Specific tissue differentiation
  • Composite tissue differentiation              
  • Histoscanning Visualization
  • Colour labeling of differentiated tissues
  • Superimposed on ultrasound volume image